Manisha Vidyavathy

Dr S Manisha Vidyavathy is working as a Professor in the Department of Ceramic Technology, Alagappa College of Technology, Anna University, Chennai – 600 025. She is heading the Department of Ceramic Technology since June 2022. She graduated in Physics from the University of Madras. She holds a post-graduation degree in Material Science and Ceramic Technology from Anna University. She obtained her PhD in Ceramic Technology from Anna University in the year 2009. Her research was on the development of niobium co- doped cubic zirconia by conventional and microwave sintering.

The current area of research is in advanced ceramics. She is working on high temperature coatings, ceramic 3D printing, ceramic membranes, and photovoltaics. She has produced 7 Ph.D scholars and 1 MS by Research and presently five students are working under her guidance. She has 30 publications to her credit. She has attended various National and International Conferences, Seminars and Workshops. She has organized 5 workshops and seminars as Co-ordinator. She is also working on various Industrial Consultancy Projects.

She is a member of the Syllabus Sub Committee (UG and PG Programmes) and Board of Studies under Faculty of Technology of Anna University. She is also acting as a Subject Expert Member and Academic Council Member for Dr J Jayalalitha Music and Fine University, Chennai. She also serves as the Subject Expert for Government Polytechnic College, Gudur, and Government Diploma College Virudachalam.

She has served in various academic and administrative responsibilities at the College level and University Level. She held various responsibilities like Deputy Director in the Centre for Academic Courses, Anna University, Programme Officer for YRC, ACTech Campus. She has also served as a Doctoral Committee Member for PHD students at SRM University, VIT Campus and University Constituent Colleges

She has visited countries like New Zealand, USA and Japan. She is the Life member of the Indian Ceramic Society and Individual Member of the American Ceramic Society.

ABSTRACT

SUSTAINABLE BONE REPLACEMENT MATERIAL : ADDITIVE MANUFACTURING OF TCP-HAP-WOLLASTONITE COMPOSITE FOR TISSUE ENGINEERING APPLICATIONS

Additive manufacturing (AM) has emerged as a transformative technology, enabling the layer-by-layer construction of three-dimensional objects directly from digital models. Among its diverse applications, ceramic additive manufacturing holds considerable promise across various sectors, including medical, aerospace, and academia. This research specifically focuses on the utilization of Direct Ink Writing (DIW) or robocasting techniques for bio ceramic applications, particularly tri-calcium phosphate (TCP), hydroxyapatite (HAP) and wollastonite as a bone replacement material in Tissue Engineering (TE). Despite advancements in AM technologies, challenges persist in optimizing printability, necessitating thorough investigations into factors such as powder-to-binder and binder-water ratios, rheological properties, and alternative binder materials. The invention introduces a novel bone replacement material that is both cost-effective and sustainable, showcasing enhanced mechanical properties. This composite material is primarily composed of TCP, HAP, and wollastonite. A significant aspect of this development is the synthesis of HAP from orange peels, which exemplifies an environmentally friendly approach and aligns with the project’s motto, “GREEN PRINT HEALTH.” This innovative production method not only minimizes waste but also effectively reduces overall production costs. To comprehensively evaluate the properties of the TCP-HAP-wollastonite composite, a series of characterization tests were conducted. X-Ray Diffraction (XRD) analysis confirmed the crystalline phases present in the composite, while in vitro bioactivity assessments demonstrated the formation of a bone-like apatite layer on the surface upon immersion in simulated body fluid (SBF). The compressive strength of the composite scaffolds was evaluated, revealing enhanced mechanical properties with the addition of wollastonite. Cytocompatibility studies using human osteoblast-like cells (MG-63) indicated that the composite supported cell attachment, viability, and proliferation.

Through systematic exploration and experimentation, this study provides valuable insights into optimizing additive manufacturing processes for bio ceramic applications, thereby laying the groundwork for future advancements in the field of bone tissue engineering. The combination of bioactivity, enhanced mechanical properties, and controlled biodegradation makes this composite a viable candidate for further in vivo evaluation and clinical translation.